The specific, favorable physiological changes that occur in the cardiovascular and metabolic systems as a result of sustained, low-to-moderate intensity aerobic exercise, specifically performed within the individual’s second ventilatory threshold (Zone 2). This adaptation is characterized by enhanced mitochondrial biogenesis, increased metabolic flexibility, and improved cardiac stroke volume. It represents a cornerstone of longevity and metabolic health protocols.
Origin
The concept is rooted in sports science and exercise physiology, utilizing the heart rate zone model to prescribe exercise intensity relative to an individual’s maximal capacity. Zone 2 denotes the intensity level where fat oxidation is maximized and lactate production is matched by clearance. Adaptation refers to the chronic, structural, and functional improvements achieved through consistent training.
Mechanism
Exercising in Zone 2 selectively stresses the slow-twitch muscle fibers, which are rich in mitochondria. This sustained metabolic demand acts as a powerful signal to increase the number and function of mitochondria, thereby enhancing the cell’s Substrate Oxidation Capacity. The improved efficiency of the heart and peripheral vasculature also lowers the resting heart rate and blood pressure, collectively optimizing systemic energy delivery and utilization.
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