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Zombie Cell Clearance

Meaning

Zombie Cell Clearance, scientifically termed senolysis or the elimination of senescent cells, is a biological process focused on the removal of cells that have ceased dividing but remain metabolically active, secreting pro-inflammatory and tissue-damaging molecules. These senescent cells, often called “zombie cells,” accumulate with age and contribute significantly to chronic inflammation, tissue dysfunction, and the development of age-related diseases. The goal of clearance strategies is to selectively induce apoptosis (programmed cell death) in these detrimental cells to rejuvenate tissue microenvironments and improve overall healthspan.