What is the Origin of Zepbound?

The term is a brand name for a drug whose active ingredient, tirzepatide, was developed based on decades of endocrinology research into incretin hormones and their role in glucose homeostasis and appetite regulation. Its clinical application is in metabolic and hormonal health. This class of medication represents a major advancement in the treatment of obesity.

What is the Mechanism of Zepbound?

As a dual GIP and GLP-1 receptor agonist, Zepbound enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying. Crucially for weight management, the drug acts centrally in the hypothalamus to reduce appetite and increase satiety. This combined mechanism leads to improved glycemic control and sustained negative energy balance.

Zepbound

Meaning

The trade name for tirzepatide, a novel pharmaceutical agent approved for chronic weight management in adults with obesity or overweight with related comorbidities. This drug functions as a dual agonist targeting both the Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-like Peptide-1 (GLP-1) receptors. It is a powerful tool in the clinical management of metabolic dysfunction and obesity.