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WHI Study Fallacy

Meaning

The WHI Study Fallacy refers to the widespread misinterpretation and overgeneralization of the initial, alarming results from the Women’s Health Initiative (WHI) study regarding hormone replacement therapy (HRT), which led to a significant, often unwarranted, decline in HRT utilization. The fallacy lies in applying the risks observed in a specific, older demographic using non-bioidentical, oral-route hormone preparations to all women, including younger, newly menopausal women who stand to benefit significantly from timely, personalized therapy. This misapplication created a generation of therapeutic hesitancy.