Skip to main content

Weight Reduction

Meaning

Weight reduction, in a clinical context, is the intentional and sustained decrease in total body mass, achieved through a negative energy balance where caloric expenditure exceeds caloric intake. This therapeutic goal is a cornerstone of managing metabolic and hormonal disorders, including type 2 diabetes, polycystic ovary syndrome (PCOS), and non-alcoholic fatty liver disease (NAFLD). Effective weight reduction, particularly of visceral fat, can lead to significant improvements in insulin sensitivity and inflammatory markers.