What is the Origin of Waking Period Growth Pulse?

This descriptive term links the waking period (the time of diurnal activity) with the growth pulse (a rapid, temporary increase in hormone secretion), distinguishing it from the well-known sleep-related GH release. It is a focus of chronobiological endocrinology and the study of exercise-induced hormonal release.

What is the Mechanism of Waking Period Growth Pulse?

The release of this pulse is often triggered by specific physiological stimuli, such as intense exercise, fasting, or a sharp drop in blood glucose, which signal the hypothalamus to release Growth Hormone-Releasing Hormone (GHRH). This GH surge then stimulates the liver to produce Insulin-like Growth Factor 1 (IGF-1), which mediates the majority of the anabolic and metabolic effects. This diurnal pulse helps mobilize fatty acids for energy, supports protein turnover, and contributes to the overall daily net protein balance.

Waking Period Growth Pulse ∞ Area

Waking Period Growth Pulse

Meaning

A clinically observed, transient surge in the pulsatile secretion of Growth Hormone (GH) that occurs during the active, waking hours, distinct from the major nocturnal peak. This specific pulse is a key physiological event for maintaining metabolic function and supporting daily anabolic needs.