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Wakefulness Drive Calibration

Meaning

Wakefulness drive calibration is the process of precisely regulating the body’s intrinsic alertness and energy levels throughout the day to ensure optimal cognitive performance and mood stability while preserving the homeostatic drive for restorative sleep at night. This calibration involves managing exposure to light, timing of stimulants, and behavioral strategies that modulate the release of wake-promoting neurotransmitters and hormones like cortisol. The goal is to avoid excessive afternoon dips or inappropriate nocturnal alertness.