Vitality Signaling Molecules are a broad class of endogenous biochemical compounds, including hormones, neuropeptides, and growth factors, that act as key communicators to regulate and maintain systemic energy, mood, and physiological function associated with youth and health. These molecules transmit information between cells and organs, orchestrating processes like tissue repair, metabolic rate, and cognitive performance. Clinical focus on these molecules involves ensuring their optimal concentration, appropriate pulsatility, and effective receptor binding to sustain a high state of well-being. Their proper function is non-negotiable for true vitality.
Origin
This term is a clinical generalization derived from the core principles of endocrinology and cell signaling, grouping together the most potent regulatory factors that decline with age. The term “vitality” emphasizes the subjective and objective health benefits derived from their optimal function. It serves as a comprehensive category for therapeutic targets in longevity medicine.
Mechanism
These molecules operate by binding to specific, high-affinity receptors on target cells, initiating a molecular cascade that modifies cellular behavior. Examples include thyroid hormone regulating metabolic rate, growth hormone stimulating tissue repair, and DHEA acting as a neurosteroid. The mechanism of support often involves precursor supplementation or the use of secretagogues to enhance the body’s natural production and release of these critical communicators.
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