The specific, clinically significant decrease in the amount of adipose tissue stored deep within the abdominal cavity, surrounding the internal organs. Visceral fat is metabolically distinct from subcutaneous fat and is a primary driver of systemic inflammation, insulin resistance, and cardiovascular risk. Targeted reduction of this specific fat depot is a critical therapeutic goal for improving metabolic health and longevity.
Origin
The term combines ‘visceral fat,’ derived from the Latin viscera meaning “internal organs,” with ‘reduction,’ signifying a decrease in quantity. The clinical importance of this term emerged from advanced imaging studies, such as DEXA and MRI, which demonstrated the unique pathological risk associated with this specific fat distribution.
Mechanism
Visceral fat reduction is primarily mediated by creating a sustained negative energy balance and optimizing the hormonal environment. A key mechanism involves improving insulin sensitivity, which reduces the lipogenic drive in the visceral adipose tissue. Furthermore, exercise and dietary changes, particularly those that manage cortisol levels, promote the lipolysis and subsequent oxidation of free fatty acids from this metabolically sensitive depot.
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