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Visceral Fat Signaling

Meaning

Visceral Fat Signaling describes the complex, adverse endocrine and paracrine communication emanating from the metabolically active adipose tissue situated deep within the abdominal cavity, surrounding the internal organs. Unlike subcutaneous fat, visceral fat secretes a unique and detrimental profile of adipokines and pro-inflammatory cytokines, which directly contribute to systemic insulin resistance, dyslipidemia, and chronic inflammation. This aberrant signaling acts as a central driver of cardiometabolic risk. Clinically, reducing visceral fat is a primary target for improving overall hormonal and metabolic health.