The physiological mechanisms and therapeutic strategies aimed at limiting or reducing the accumulation of visceral fat, which is the metabolically active adipose tissue surrounding internal organs in the abdominal cavity. Clinical control of this deposition is paramount because excess visceral fat is strongly correlated with insulin resistance, chronic inflammation, and increased metabolic risks. Hormonal balance, particularly insulin and cortisol regulation, plays a dominant role in this control.
Origin
The term links “visceral fat deposition,” referring to the accumulation of fat around the viscera, with “control,” indicating a management objective. The clinical distinction between subcutaneous and visceral fat gained significance with the realization that visceral fat is an endocrine organ itself, secreting adipokines that negatively impact systemic health.
Mechanism
Visceral Fat Deposition Control is largely mediated by the regulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis and insulin signaling. Chronic stress-induced cortisol preferentially promotes the differentiation of pre-adipocytes into visceral fat cells. Effective control involves improving insulin sensitivity to reduce lipogenesis and lowering cortisol exposure to decrease the central accumulation of adipose tissue, thereby mitigating the release of pro-inflammatory adipokines.
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