What is the Origin of Visceral Fat?

The term combines "visceral," from the Latin viscera meaning "internal organs," and "fat," denoting its composition as adipose tissue. This specific classification emerged as advanced diagnostic imaging revealed the distinct, detrimental pathophysiological role of intra-abdominal fat compared to peripheral fat stores in the arms and legs.

What is the Mechanism of Visceral Fat?

Visceral fat functions as a highly dysregulated endocrine organ, readily undergoing lipolysis and releasing free fatty acids directly into the portal circulation, which then burdens the liver. Crucially, it secretes a disproportionate amount of pro-inflammatory adipokines, such as IL-6 and TNF-alpha, that drive systemic inflammation. This inflammatory and metabolic mechanism directly impairs insulin signaling in the liver and muscle, leading to profound insulin resistance and metabolic dysfunction.

Visceral Fat

Meaning

Visceral fat is a type of metabolically active adipose tissue stored deep within the abdominal cavity, closely surrounding vital internal organs such as the liver, pancreas, and intestines. Clinically, excess visceral fat is considered a far greater health risk than subcutaneous fat, as it is strongly correlated with systemic inflammation, profound insulin resistance, and the development of metabolic syndrome. Accurate measurement of this specific fat depot is a critical prognostic indicator for cardiovascular and endocrine health across all populations.

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