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Visceral Adiposity Remodeling

Meaning

Visceral Adiposity Remodeling refers to the targeted intervention aimed at altering the composition and function of fat stored deep within the abdominal cavity, shifting it from a pro-inflammatory, endocrine-disrupting phenotype to a healthier, less metabolically active state. This process focuses not just on fat mass reduction but on improving the adipocyte’s hormonal signaling capabilities, specifically reducing ectopic lipid secretion. Successful remodeling mitigates the chronic low-grade inflammation that drives peripheral insulin resistance and dampens steroidogenesis. It is a critical objective in managing metabolic syndrome through hormonal optimization.