Visceral Adiposity Regression is the clinical objective of actively reducing the amount of visceral fat, which is the metabolically active adipose tissue stored deep within the abdominal cavity, surrounding the vital internal organs. This regression is a crucial therapeutic goal because visceral adiposity is strongly and independently associated with a significantly increased risk of insulin resistance, cardiovascular disease, and chronic systemic inflammation. Successful regression measurably improves key metabolic health markers.
Origin
This term is rooted in metabolic medicine and body composition analysis, combining “visceral adiposity” (internal abdominal fat) with “regression” (a return to a less severe or diminished state). It highlights the clinical importance of fat distribution and type over merely total body weight.
Mechanism
Regression is primarily achieved by creating a sustained, controlled negative energy balance and modulating hormonal signals that favor lipolysis, or fat breakdown, over lipogenesis, or fat storage, specifically in the visceral compartment. Hormones like growth hormone and adiponectin play a regulatory role in this process. Lifestyle interventions, particularly targeted dietary changes and consistent aerobic exercise, are highly effective in stimulating the release of fatty acids from these stores, leading to a measurable and clinically significant reduction in central adiposity.
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