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Visceral Adiposity and Hormones

Meaning

Visceral Adiposity and Hormones describes the critical, bidirectional relationship between the accumulation of metabolically active fat tissue surrounding internal organs and the systemic dysregulation of the endocrine system. Visceral fat is not merely an inert storage depot; it functions as an active endocrine organ, secreting adipokines and inflammatory cytokines that directly interfere with insulin signaling, sex hormone metabolism, and the HPA axis. Clinically, excessive visceral adiposity is a powerful predictor of cardiometabolic risk and is directly associated with conditions like low testosterone in men and estrogen dominance in women. Managing this fat is central to hormonal health.