A subjective yet clinically relevant state characterized by robust physical vitality, mental acuity, and a high capacity for sustained physiological effort and resilience. Vigor is the observable expression of underlying hormonal and metabolic optimization. It signifies a high level of functional engagement.
Origin
From the Latin vigor, meaning strength or force, this term encapsulates the functional expression of optimal health across multiple physiological domains. It represents the successful integration of physical and mental capacities. The concept implies energetic output potential.
Mechanism
High vigor correlates strongly with optimal mitochondrial efficiency, adequate anabolic hormone profiles (e.g., sufficient IGF-1 and testosterone), and efficient energy substrate mobilization, reflecting a highly adaptive endocrine and metabolic status. Strong neuroendocrine signaling supports the necessary drive for sustained effort. This state requires the endocrine system to be functioning without significant suppression or dysregulation.
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