The measure of a person’s ability to successfully encode, store, and retrieve information presented through language, encompassing both auditory and written modalities. Integrity in this context signifies the accuracy, speed, and durability of these memory processes, which are crucial for daily communication, learning, and cognitive function. This cognitive domain is notably sensitive to the neuroendocrine environment, particularly the balance of estrogen, testosterone, and thyroid hormones.
Origin
The term is a construct from neuropsychology, where memory is systematically fractionated into different types, such as verbal versus spatial memory. “Integrity” denotes the functional health and reliability of the underlying neural circuits, primarily located in the temporal lobe and hippocampus. Research in neuroendocrinology has established the direct link between hormonal status and the functional integrity of these brain regions.
Mechanism
Verbal memory integrity is mechanistically supported by optimal synaptic plasticity in the hippocampus, a process significantly modulated by steroid hormones. Estrogen, for instance, has been shown to enhance synaptic connectivity and
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