What is the Origin of Vasopressin Receptor?

The term combines vasopressin, the hormone name, with receptor, derived from the Latin recipere, meaning to receive. The name vasopressin itself reflects its action of vaso-constriction and pressin-g (raising) blood pressure.

What is the Mechanism of Vasopressin Receptor?

The V2 receptor subtype, located primarily in the renal collecting ducts, utilizes a G-protein coupled mechanism to increase cyclic AMP (cAMP), leading to the insertion of aquaporin channels into the cell membrane. This action enhances water reabsorption, conserving fluid and concentrating the urine. The V1a and V1b subtypes, found in the vasculature and anterior pituitary, respectively, mediate vasoconstriction and ACTH release via different intracellular signaling pathways.

Vasopressin Receptor ∞ Area

Vasopressin Receptor

Meaning

A Vasopressin Receptor is a specific, high-affinity protein structure located on the surface of target cells that binds to the neurohypophyseal hormone vasopressin, also known as Antidiuretic Hormone (ADH). These receptors are classified into several subtypes (V1a, V1b, V2), each mediating distinct physiological effects. Their function is crucial for regulating water balance, blood pressure, and central nervous system functions, including social behavior and stress response.