Vasopressin Effects are the broad and vital physiological actions mediated by the neurohormone vasopressin, also known as Antidiuretic Hormone (ADH), which is a peptide hormone synthesized in the hypothalamus and released by the posterior pituitary. Its primary functions are the meticulous regulation of body water balance, systemic blood pressure, and vascular tone. The effects of vasopressin are absolutely critical for maintaining fluid homeostasis and plasma osmolality in the human body.
Origin
The term combines the hormone name “Vasopressin,” derived from its observed action of “pressing” or constricting “vessels” to raise blood pressure, with “effects,” describing its biological outcomes. The alternate name, ADH, emphasizes its primary action on the kidney to prevent excessive water loss. This dual nomenclature reflects its two major physiological roles.
Mechanism
Vasopressin acts through two primary receptor subtypes: it binds to V2 receptors located in the renal collecting ducts, which initiates a cascade that increases the insertion of aquaporin channels, thus maximizing water reabsorption and conserving body fluid. Simultaneously, it acts on V1 receptors found on vascular smooth muscle cells, triggering potent vasoconstriction. This dual mechanism ensures precise control over both circulating volume and systemic arterial pressure.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.