What is the Origin of Vascular Health Integrity?

This term is a clinical concept in cardiology and longevity medicine, combining the structural component "Vascular Health" with the functional quality of "Integrity." It signifies the robust, undamaged state of the blood vessel system.

What is the Mechanism of Vascular Health Integrity?

Integrity is maintained by the continuous production of vasodilators like nitric oxide by healthy endothelial cells, which keeps the vessel lumen open and prevents platelet aggregation. Hormones, such as estrogen and testosterone, play a crucial role by modulating endothelial function and reducing systemic inflammation. When this mechanism is compromised, oxidative stress and chronic inflammation lead to endothelial dysfunction and the stiffening of arteries, significantly increasing cardiovascular risk and impairing tissue perfusion.

Vascular Health Integrity ∞ Area

Vascular Health Integrity

Meaning

The optimal functional and structural condition of the entire circulatory network, including the arteries, veins, and microvasculature, characterized by a non-thrombogenic endothelium, appropriate arterial elasticity, and efficient regulation of blood pressure and blood flow. High integrity is a prerequisite for systemic health, ensuring adequate oxygen and nutrient delivery to all tissues, including the brain and endocrine glands. Loss of integrity is a major precursor to age-related disease.