Skip to main content

Vaginal Progesterone

Meaning

A specific route of administration for the bio-identical hormone progesterone, delivered directly to the vaginal mucosa via a suppository, cream, or gel formulation. This method is clinically utilized to achieve targeted endometrial protection and systemic hormonal effects, often resulting in lower systemic peak concentrations compared to oral administration due to reduced first-pass hepatic metabolism. It is a precise method for hormone replacement therapy.