Uric Acid Control is the clinical management strategy focused on maintaining circulating uric acid levels within an optimal physiological range to mitigate its role as a metabolic danger signal and a driver of inflammation. While historically linked primarily to gout, contemporary research highlights uric acid’s critical involvement in metabolic syndrome, hypertension, and cardiovascular risk. Effective control involves a combination of dietary, nutraceutical, and, when necessary, pharmacological interventions to regulate its production and excretion. Achieving this control is an essential component of comprehensive metabolic and longevity health protocols.
Origin
The term is rooted in biochemistry and clinical pathology, where uric acid is the end product of purine metabolism. The shift to “control” rather than just “treatment” reflects the evolving understanding of uric acid’s pleiotropic effects beyond crystal deposition. Research demonstrating its role in mitochondrial dysfunction and activation of the inflammasome solidified its status as a critical, modifiable biomarker in proactive health management.
Mechanism
Control is achieved by modulating the enzyme xanthine oxidase, which catalyzes the final
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