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Tubular Injury Biomarkers

Meaning

Specific proteins or molecules released into the urine or blood that serve as early, sensitive indicators of damage to the renal tubules, the structures in the kidney responsible for reabsorbing essential substances and concentrating urine. Unlike traditional markers like serum creatinine, these newer biomarkers, such as Kidney Injury Molecule-1 (KIM-1) or Neutrophil Gelatinase-Associated Lipocalin (NGAL), detect acute kidney injury much earlier, allowing for prompt clinical intervention. Monitoring these markers is vital in hormonal health for patients on therapies with potential nephrotoxic side effects.