What is the Origin of TRT Therapy?

This therapy has its roots in endocrinology, developing from early attempts to treat male hypogonadism. It is now a refined protocol guided by evidence regarding androgen receptor signaling.

What is the Mechanism of TRT Therapy?

The mechanism involves bypassing deficient endogenous testicular or adrenal production by supplying exogenous testosterone, usually via injection, transdermal application, or pellets, to maintain stable serum concentrations. Proper titration is essential to achieve symptom relief while minimizing negative feedback on the HPG axis and managing hematocrit levels.

TRT Therapy

Meaning

TRT Therapy, or Testosterone Replacement Therapy, is a clinically supervised intervention involving the exogenous administration of testosterone to individuals diagnosed with clinically significant hypogonadism to restore circulating levels toward a physiological optimum. This aims to alleviate symptoms related to low androgen status.