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Trinucleotide Repeat Length

Meaning

Trinucleotide repeat length refers to the number of consecutive repetitions of a three-nucleotide DNA sequence within a specific gene, such as the CAG repeat in the androgen receptor gene. In genetics, variations in the length of these repeats can significantly influence gene function, particularly protein structure and stability. Clinically, an abnormal expansion of these repeat lengths is associated with a class of neurodegenerative and hormonal disorders.