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Trauma Response

Meaning

Trauma Response, in a broad clinical and physiological sense, refers to the acute and chronic systemic adaptations that occur following exposure to a physically or psychologically overwhelming event. Physiologically, this involves a profound, prolonged activation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to dysregulated cortisol secretion and altered sympathetic nervous system tone. This chronic activation can lead to systemic inflammation, hormonal imbalances, and a reduced capacity for homeostatic regulation. Understanding the trauma response is critical for addressing its downstream effects on metabolic and endocrine health.