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Transforming Growth Factor-Beta

Meaning

Transforming Growth Factor-Beta (TGF-β) is a pleiotropic protein belonging to a superfamily of cytokines, which are essential cell-signaling molecules that regulate a vast array of cellular functions, including growth, proliferation, differentiation, and programmed cell death (apoptosis). In the context of hormonal health and tissue integrity, TGF-β is critically involved in wound healing, immune suppression, and the promotion of extracellular matrix deposition. Its dysregulation can lead to pathological conditions like tissue fibrosis and excessive scarring.