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Transferrin Saturation

Meaning

Transferrin Saturation (TSAT) is a clinical laboratory value that represents the percentage of transferrin, the primary iron-transport protein in the blood, that is currently bound to iron. This metric is a crucial indicator of iron status, reflecting the balance between iron absorption, storage, and utilization throughout the body. Abnormal TSAT levels, particularly high saturation, can signal potential iron overload or hemochromatosis, which can be detrimental to endocrine function and overall health.