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Transdermal Testosterone

Meaning

Transdermal Testosterone refers to a non-invasive pharmaceutical delivery method for exogenous testosterone replacement therapy, involving the direct application of the hormone in a gel, cream, or patch formulation onto the skin surface for systemic absorption. This route is clinically advantageous because it bypasses the extensive first-pass hepatic metabolism that occurs with oral administration, offering a more favorable pharmacokinetic profile. It is a common modality utilized for both male and female patients requiring sex steroid modulation.