What is the Origin of Transcutaneous Vagus Nerve Stimulation?

This technique is a non-surgical evolution of traditional Vagus Nerve Stimulation (VNS), which was initially developed as an implanted device for epilepsy and depression. The term 'transcutaneous' is derived from the Latin trans (across) and cutis (skin), highlighting the non-invasive delivery method.

What is the Mechanism of Transcutaneous Vagus Nerve Stimulation?

Stimulation of the vagus nerve activates the cholinergic anti-inflammatory pathway, which sends signals to the spleen and other immune organs to inhibit the release of pro-inflammatory cytokines. By enhancing vagal tone, tVNS helps to stabilize the HPA axis, reducing chronic cortisol exposure and improving heart rate variability. This modulation of the autonomic-endocrine-immune axis offers a powerful, non-pharmacological strategy for improving systemic resilience.

Transcutaneous Vagus Nerve Stimulation ∞ Area

Transcutaneous Vagus Nerve Stimulation

Meaning

Transcutaneous Vagus Nerve Stimulation (tVNS) is a non-invasive neuromodulation technique that delivers low-level electrical pulses to the afferent fibers of the vagus nerve via electrodes placed on the skin, typically at the ear or neck. The clinical application aims to modulate autonomic nervous system balance, promoting parasympathetic tone over sympathetic overdrive. This therapeutic approach is gaining recognition for its potential to mitigate chronic inflammation and regulate the stress response.