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Tolerogenic Adjuvants

Meaning

Tolerogenic adjuvants are specific pharmacological or immunological agents included within a formulation, meticulously designed not to stimulate an aggressive immune response but rather to actively promote a state of immunological tolerance to the co-administered antigen or therapeutic substance. In the context of advanced hormonal therapy, this sophisticated approach aims to prevent unwanted immune reactions against the hormone or its carrier, particularly in complex, long-acting delivery systems. They help the body’s immune system recognize the therapeutic agent as ‘self,’ thereby maintaining essential immune quietude and preventing rejection.