Titration Phase

Meaning

The Titration Phase is the controlled, clinical period during which the dosage of a therapeutic agent, particularly a hormone replacement compound or a new medication, is incrementally and systematically adjusted to achieve the optimal therapeutic effect. This phase is essential to find the patient’s individual biological threshold, maximizing efficacy while minimizing the risk of adverse side effects. Precise titration requires meticulous monitoring of both subjective symptoms and objective biochemical markers. It is a necessary process to personalize the final, stable maintenance dose.

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