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Tissue Substrate Replenishment

Meaning

Tissue Substrate Replenishment is the clinical and nutritional strategy focused on systematically restoring the intracellular concentration of essential metabolic precursors, cofactors, and structural molecules within specific organs and endocrine glands to support optimal function. This is critical when chronic stress, disease, or inadequate diet has led to the depletion of these fundamental biochemical building blocks, thereby compromising tissue capacity for synthesis and repair. The goal is to provide the necessary raw materials for cellular and hormonal synthesis.