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Tissue Specific Receptor Expression

Meaning

Tissue Specific Receptor Expression refers to the unique and variable distribution, concentration, and functional state of hormone receptors on the surface or within the cells of different target tissues throughout the body. This differential expression dictates how a specific hormone, such as testosterone or estrogen, will exert its effects in the liver, muscle, bone, or brain. Clinical strategies must account for this variability, as it explains why a single hormone level can produce different systemic effects in various individuals or at different life stages. Understanding this specificity is crucial for precision endocrinology.