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Tissue Sensitivity Enhancement

Meaning

This physiological and clinical objective focuses on improving the responsiveness of target cells and organs to the circulating levels of key hormones, rather than solely increasing the hormone concentration itself. Enhancement is achieved by increasing the density or affinity of hormone receptors on the cell surface or by optimizing the post-receptor signaling pathways within the cell. This strategy is particularly relevant for hormones like insulin and thyroid hormone, where resistance often precedes overt deficiency. Improving sensitivity is a fundamental strategy for restoring youthful hormonal function and metabolic health.