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Tissue Sensitivity Adjustment

Meaning

Tissue sensitivity adjustment is the clinical strategy of modulating the responsiveness of target cells and organs to circulating hormones or signaling molecules. This process involves upregulating or downregulating the number or affinity of specific receptors on the cell surface to enhance or diminish the biological effect of a given signal concentration. The goal is to correct cellular resistance or hypersensitivity, thereby optimizing the effectiveness of endogenous or exogenous compounds.