Tissue Regeneration is the physiological process through which damaged or lost cells, tissues, or organs are replaced or repaired to restore their original structure and function. This complex biological renewal is essential for healing and maintaining tissue integrity over time. It relies heavily on precise cellular communication.
Origin
The term combines the biological unit (’tissue’) with the concept of renewal or restoration (‘regeneration’). It defines the body’s innate capacity to rebuild itself.
Mechanism
Successful regeneration involves the controlled activation and proliferation of local progenitor cells, guided by appropriate growth factor signaling, often including components regulated by the Somatotropic Axis. Efficient regeneration requires a supportive extracellular matrix environment.
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