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Tissue Matrix Remodeling

Meaning

Tissue Matrix Remodeling is the dynamic, continuous physiological process involving the degradation and synthesis of the extracellular matrix (ECM)—the non-cellular component of tissues—which provides structural support, regulates cell function, and is crucial for wound healing and tissue repair. In hormonal health, this remodeling is heavily influenced by growth factors, sex hormones, and inflammatory signals, impacting the integrity of skin, bone, and connective tissues. Efficient remodeling is essential for maintaining youthful tissue elasticity and strength.