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Tissue Maintenance Fidelity

Meaning

Tissue Maintenance Fidelity describes the clinical concept of ensuring that the continuous processes of cellular turnover, repair, and regeneration within all tissues occur with high precision and minimal accumulation of error or damage. High fidelity implies that new cells and extracellular matrix components are synthesized correctly, matching the original, healthy blueprint, which is crucial for long-term organ function and longevity. A decline in fidelity is a fundamental characteristic of biological aging and leads to tissue degradation and functional decline. The goal is to optimize the molecular machinery responsible for this renewal process.