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Time-Sensitive Physiological Windows

Meaning

Time-Sensitive Physiological Windows are specific, brief periods within the 24-hour circadian cycle or the monthly menstrual cycle during which the body exhibits maximal responsiveness to a particular stimulus, such as a hormone, nutrient, or exercise. These windows are governed by the rhythmic expression of receptors and enzymes, making the timing of an intervention critically important for its therapeutic efficacy. Examples include the enhanced insulin sensitivity following exercise or the optimal timing for melatonin administration relative to the dim light melatonin onset (DLMO). Precision timing is therefore a fundamental principle in advanced hormonal and metabolic optimization.