The measurable success and beneficial physiological outcomes achieved by limiting daily caloric intake to a specific, consistent window of time, typically 8-12 hours, without necessarily reducing total caloric intake. Efficacy is assessed by objective metrics such as improved insulin sensitivity, enhanced metabolic flexibility, reduced systemic inflammation, and favorable modulation of circadian hormone rhythms, notably cortisol and melatonin. This is a powerful lifestyle intervention used to optimize metabolic health and cellular repair processes.
Origin
This concept stems from chronobiology and metabolic research, recognizing that the timing of nutrient intake significantly influences the body’s internal clocks and metabolic pathways. The ‘Efficacy’ component highlights the therapeutic potential of this strategy to improve health markers independent of total weight loss. It is a clinically recognized form of intermittent fasting that leverages the body’s natural diurnal cycles.
Mechanism
The efficacy is mediated by extending the daily fasting period, which triggers a metabolic switch from glucose-based energy to fat-based energy (ketogenesis) and activates cellular repair
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