Thyroid Performance is the measure of the Hypothalamic-Pituitary-Thyroid (HPT) axis efficiency in producing, converting, and effectively utilizing thyroid hormones to govern systemic energy expenditure and cellular metabolism.
Origin
This is a direct clinical metric used in endocrinology to assess the functional output of the thyroid gland and associated regulatory centers.
Mechanism
Optimal performance requires efficient T4 to T3 conversion, mediated by deiodinase enzymes, ensuring that tissues receive the metabolically active triiodothyronine necessary for mitochondrial respiration and thermogenesis.
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