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Thyroid Hormone Excess

Meaning

Thyroid hormone excess, clinically termed hyperthyroidism or thyrotoxicosis, is a pathological state that results from inappropriately high circulating concentrations of the active thyroid hormones, primarily triiodothyronine (T3) and thyroxine (T4). This hormonal overabundance causes a profound and generalized acceleration of the body’s basal metabolic rate, impacting the function of nearly every single organ system. Characteristic symptoms often include unintended weight loss, significant tachycardia, excessive heat intolerance, and profound anxiety, all reflecting a state of systemic hypermetabolism. Clinically, identifying and managing the underlying cause of this hormonal overactivity is crucial for preventing severe, life-threatening complications like atrial fibrillation or thyroid storm.