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Thyroid Hormone Axis Evaluation

Meaning

Thyroid Hormone Axis Evaluation is the comprehensive clinical and laboratory assessment of the Hypothalamic-Pituitary-Thyroid (HPT) axis, the interconnected feedback loop that controls thyroid hormone production and function. This evaluation extends beyond basic TSH measurement to include free and total levels of T4 and T3, as well as reverse T3 and thyroid antibodies, to diagnose subtle or overt thyroid dysfunction. A thorough evaluation provides a detailed picture of the gland’s output, peripheral hormone conversion efficiency, and autoimmune status. This meticulous approach is essential for identifying the root cause of symptoms related to energy, metabolism, and mood.