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Thyroid Function Recalibration

Meaning

The clinical process of precisely adjusting therapeutic interventions, including lifestyle, nutritional support, and hormone replacement, to restore the entire Hypothalamic-Pituitary-Thyroid (HPT) axis to its optimal homeostatic set point. Recalibration moves beyond simply normalizing TSH levels to ensure ideal free T3 and T4 concentrations and robust thyroid receptor sensitivity at the cellular level. This is a personalized strategy to address both overt and subclinical thyroid dysfunction.