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Thyroid Axis Efficiency

Meaning

Thyroid Axis Efficiency is the measure of how effectively the entire Hypothalamic-Pituitary-Thyroid (HPT) axis functions, encompassing TSH secretion, the conversion of T4 to active T3 in peripheral tissues, and the appropriate cellular response to circulating thyroid hormones. High efficiency ensures optimal basal metabolic rate regulation, energy expenditure, and thermal homeostasis across the body. Suboptimal efficiency, even within conventionally “normal” ranges, can lead to pervasive fatigue and metabolic sluggishness. We assess this axis for optimal functional output.