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Thromboembolism

Meaning

Thromboembolism is a serious clinical event characterized by the formation of a blood clot, known as a thrombus, within a blood vessel, which subsequently breaks loose and travels through the bloodstream as an embolus, potentially lodging in a smaller vessel and obstructing blood flow. This vascular obstruction can lead to life-threatening conditions such as pulmonary embolism or stroke. Hormonal factors, particularly certain exogenous estrogens and androgens, can influence the coagulation cascade, thereby altering the individual’s inherent risk for thromboembolism. Clinical vigilance is essential when prescribing hormone therapy, especially in patients with pre-existing risk factors.