What is the Origin of Threat Response?

Rooted deeply in evolutionary biology and stress physiology, this response is a conserved reaction pattern to perceived environmental challenges. It is the initial phase of the general adaptation syndrome described by Selye. The system is wired for rapid mobilization.

What is the Mechanism of Threat Response?

The process involves rapid release of norepinephrine and epinephrine from the adrenal medulla, preparing tissues for fight or flight. Following this, the hypothalamus signals the pituitary to release ACTH, leading to sustained cortisol release which mobilizes glucose stores. Chronically engaging this mechanism is detrimental to endocrine health.

Threat Response

Meaning

The Threat Response is the immediate, stereotyped physiological mobilization orchestrated by the central nervous system upon the perception of physical or psychological danger, engaging the sympathetic nervous system and initiating the HPA axis cascade. This ancient survival mechanism prioritizes immediate defense over long-term metabolic regulation. It is the body’s alarm system.