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Thiamine Deficiency

Meaning

Thiamine deficiency, clinically known as Beriberi or Wernicke-Korsakoff syndrome in its severe forms, is a state resulting from inadequate intake or absorption of thiamine (Vitamin B1), an essential water-soluble vitamin. Thiamine is a critical cofactor for several key enzymes in carbohydrate and amino acid metabolism, playing an indispensable role in energy production, particularly in the brain and nervous system. A deficiency can lead to profound neurological, cardiovascular, and metabolic derangements, impacting hormonal regulation and overall cellular function. Early recognition and supplementation are crucial to prevent irreversible damage.