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Thermotolerance Acquisition

Meaning

Thermotolerance Acquisition is the rapid, transient state of enhanced cellular and systemic resistance to subsequent, potentially damaging heat stress, achieved immediately following a brief, non-damaging thermal pre-conditioning exposure. This acute protective state is a critical, evolutionarily conserved pro-survival mechanism that actively shields vital proteins and cellular machinery from denaturation and aggregation. It is a direct, adaptive response utilized in structured heat exposure protocols to maximize cellular resilience and minimize thermal-induced damage.